Neurodevelopmental disorders (NDDs), such as autism spectrum disorder (ASD), represent a group of highly prevalent, early onset conditions featured by neural and behavioral impairments with a strong genetic basis. Effective treatments for patients with ASD have yet to be developed due to the limited understanding of their pathophysiology and the lack of animal models that recapitulate neural and behavioral traits. Recent advances in genetic technology, such as viral-mediated transgene and CRISPR-Cas9-mediated gene-editing, enabled the engineering of nonhuman primate models of genetic disorders. This provides us with an unprecedented opportunity to better approximate the neural and behavioral manifestations of NDDs in the affected human individual.

Direct Link:

Journal: Translational Research Methods in Neurodevelopmental Disorders 2022 (pp. 235-262)

Keywords: behavioural characterization, gene editing, genotyping, neurodevelopmental disorders, nonhuman primates, Sleep,

Applications: Sleep,

CamNtech Reference: M22058

Back to Search Results

UK & International customers

CamNtech Ltd.
Manor Farm
PE28 9JD, UK

US customers

CamNtech Inc.
630 Boerne Stage Airfield,
Texas 78006,


© 2024 CamNtech Ltd and CamNtech Inc

Company information

Registered in England No. 2221302
VAT No: GB486 3019 34

Privacy Policy