MotionWatch Archives

A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania

by Admin1 | Sep 9, 2020

Rationale Lithium is an effective prophylactic and anti-manic treatment in bipolar disorder; however, its use is declining through perceived poor tolerance and toxicity. Lithium inhibits inositol monophosphatase (IMPase), a probable key therapeutic mechanism. The...

Prediction of individual differences in circadian adaptation to night work among older adults: application of a mathematical model using individual sleep-wake and light exposure data

by Admin1 | Sep 6, 2020

Circadian misalignment remains a distinct challenge for night shift workers. Variability in individual sleep-wake/light-dark patterns might contribute to individual differences in circadian alignment in night shift workers. In this simulation study, we compared the...

Multiple sclerosis-related fatigue: the role of impaired corticospinal responses and heightened exercise fatigability

by Admin1 | Sep 2, 2020

It is unclear whether motor fatigability and perceived fatigue share a common pathophysiology in people with multiple sclerosis (PwMS). This cross-sectional investigation explored the relationship between the mechanisms of motor fatigability from cycling and fatigue...

An Automatic Estimation of the Rest-Interval for MotionWatch8© Using Uniaxial Movement and Lux Data

by Admin1 | Aug 24, 2020

Poor sleep is linked with chronic conditions common in older adults, including diabetes, heart disease, and dementia. Valid and reliable field methods to objectively measure sleep are thus greatly needed to examine how poor sleep impacts older adults. Wrist-worn...

Binocular Vision, Visual Function, and Pupil Dynamics in People Living With Dementia and Their Relation to the Rate of Cognitive Decline and Structural Changes Within the Brain: Protocol for an Observational Study

by Admin1 | Aug 10, 2020

Background: Visual impairment is a common comorbidity in people living with dementia. Addressing sources of visual difficulties can have a significant impact on the quality of life for people living with dementia and their caregivers. Depth perception problems are...

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A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania

Prediction of individual differences in circadian adaptation to night work among older adults: application of a mathematical model using individual sleep-wake and light exposure data

Multiple sclerosis-related fatigue: the role of impaired corticospinal responses and heightened exercise fatigability

An Automatic Estimation of the Rest-Interval for MotionWatch8© Using Uniaxial Movement and Lux Data

Binocular Vision, Visual Function, and Pupil Dynamics in People Living With Dementia and Their Relation to the Rate of Cognitive Decline and Structural Changes Within the Brain: Protocol for an Observational Study

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A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania

Prediction of individual differences in circadian adaptation to night work among older adults: application of a mathematical model using individual sleep-wake and light exposure data

Multiple sclerosis-related fatigue: the role of impaired corticospinal responses and heightened exercise fatigability

An Automatic Estimation of the Rest-Interval for MotionWatch8© Using Uniaxial Movement and Lux Data

Binocular Vision, Visual Function, and Pupil Dynamics in People Living With Dementia and Their Relation to the Rate of Cognitive Decline and Structural Changes Within the Brain: Protocol for an Observational Study

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