Visuospatial Working Memory under Fatigue: Observations with Cerebral Hemodynamics and Heart Rate Variability

Visuospatial working memory (WM) is a central component of human executive function within safety-critical systems, where the interactions between fatigue due to timeon-task and WM capacity remain critical yet under-explored dimensions. In this work, we investigated the temporal dynamics of brain activation, functional connectivity, and heart-rate variability (HRV) during a fatiguing visuospatial two-back test. We recruited sixteen participants who were subject to this protocol while we captured their neurophysiological data through near …