The obesity paradox, whereby being overweight or obese during mid-life is associated with higher rates of dementia in later life, while low body mass index (BMI) in older populations is associated with a higher risk of dementia, has been demonstrated in multiple studies of patients with Alzheimer’s disease (Fitzpatrick et al., 2009). In another neurodegenerative disorder, frontotemporal dementia (FTD), classic descriptions suggest a different pattern, specifically weight gain with disease onset due to hyperphagia and increased sweet intake. However, BMI has not been found to correlate with food intake in FTD, raising the possibility of altered metabolism in patients…

Direct Link: https://doi.org/10.1093/brain/aww312

Journal: Brain. 2017 Jan 1;140(1):10-2.

Keywords: energy expenditure, frontotemporal dementia, Heart Rate, metabolism, obesity, tachycardia,

Applications: Energy Expenditure,

CamNtech Reference: AH17007

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