Publications

CamNtech Research Library

CamNtech products have been trusted by specialist researchers for over 25 years.

Our research library contains peer reviewed publications citing the use of our devices.

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Found 91 Results

Clock Genes Profiles as Diagnostic Tool in (Childhood) ADHD—A Pilot Study

Attention deficit hyperactivity disorder (ADHD) is a very common disorder in children and adults. A connection with sleep disorders, and above all, disorders of the circadian rhythm are the subject of research and debate. The circadian system can be represented on different levels. There have been a variety of studies examining 24-h rhythms at the […]

Related Product: MotionWatch

Publication Date: September 5, 2022


Changes in Circadian Rhythmicity during COVID-19 Pandemic Lockdowns

Background: For many people, the COVID-19 pandemic was an intrusion into their daily activities and their work and personal lives. Due to this pandemic, people were forced to spend their time mainly in their homes, which significantly reduced their activities. These restrictions have had a major impact on people, both in terms of their physical […]

Related Product: MotionWatch

Publication Date: September 2, 2022


Intake of l-serine before bedtime prevents the delay of the circadian phase in real life

Background It has been shown in laboratory experiments using human subjects that ingestion of the non-essential amino acid L-serine before bedtime enhances the advance of circadian phase induced by light exposure the next morning. In the present study, we tested the effect of ingestion of L-serine before bedtime on circadian phase in real life and […]

Related Product: MotionWatch

Publication Date: August 26, 2022


Daytime rest: Association with 24‐h rest‐activity cycles, circadian timing and cognition in older adults

Growing epidemiological evidence points toward an association between fragmented 24-h rest–activity cycles and cognition in the aged. Alterations in the circadian timing system might at least partially account for these observations. Here, we tested whether daytime rest (DTR) is associated with changes in concomitant 24-h rest probability profiles, circadian timing and neurobehavioural outcomes in healthy […]

Related Product: MotionWatch

Publication Date: July 29, 2022


MotionWatch 8 Wrist Activity and Light Analysis: from ambulatory recording toward real life monitoring

Background The Author’s interest is to apply physiological recordings for real-life, long-term and unsupervised monitoring as a complement to telemedicine and home care. This means the search for parameters that will be used to alert when some kind of support will be needed. To this end, the Author has recorded and published an appropriate Motionwatch8 […]

Related Product: MotionWatch

Publication Date: June 23, 2022


Bright Light Increases Alertness and Not Cortisol in Healthy Men: A Forced Desynchrony Study Under Dim and Bright Light

Light-induced improvements in alertness are more prominent during nighttime than during the day, suggesting that alerting effects of light may depend on internal clock time or wake duration. Relative contributions of both factors can be quantified using a forced desynchrony (FD) designs. FD designs have only been conducted under dim light conditions (

Related Product: MotionWatch

Publication Date: June 10, 2022


Associations between circadian misalignment and telomere length in BD: an actigraphy study

Background Life expectancy is significantly decreased in bipolar disorder (BD). This is associated with accelerated cellular aging which can be estimated by telomere length (TL). However, specific determinants of shorter TL in BD are under-explored. This study examines whether circadian misalignment (i.e. mismatch between preferred and actual phase of circadian activity rhythms) is associated with […]

Related Product: MotionWatch

Publication Date: May 27, 2022


Rest-Activity Circadian Rhythm and Light Exposure Using Wrist Actigraphy in ICU Patients

Actigraphy (ACTG) is easy to use and has proved reliable in non-critical populations of patients. It has been used to track circadian rest-activity cycles and to identify states of wakefulness and sleep [1]. A more recent study has found that ACTG have a moderate level of agreement with PSG in distinguishing between sleep and wakeful […]

Related Product: MotionWatch

Publication Date: April 18, 2022


Time Course of Motor Sleep Inertia Dissipation According to Age

Sleep inertia (SI) refers to a complex psychophysiological phenomenon observed after morning awakening that can be described as the gradual recovery of waking-like status after a night of sleep. The time course of SI dissipation in an everyday life condition is little studied. The present study aims to investigate the SI dissipation in motor activity, […]

Related Product: MotionWatch

Publication Date: March 23, 2022


Impact of sleep timing on attention, sleepiness, and sleep quality among real-life night shift workers with shift work disorder: a cross-over clinical trial

Study objectives: To examine the effect of sleep timing intervention on sleep quality, attention, and sleepiness at work among night shift workers with shift work disorder. Methods: We recruited 60 real-life night shift workers through advertisements to participate this cross-over clinical trial. Shift work disorder was confirmed with interview and sleep log. Participants were designated […]

Related Product: MotionWatch

Publication Date: March 10, 2022


Circadian and Sleep Modulation of Dreaming in Women with Major Depression

Growing evidence indicates an association between reduced dream recall and depressive symptomatology. Here, we tested the prediction that reduced dream recall in individuals experiencing major depressive disorder (MDD) is due to alterations in circadian and sleep processes. Nine young healthy women (20–31 years) and eight young unmedicated women (20–31 years) diagnosed with MDD underwent a […]

Related Product: MotionWatch

Publication Date: February 28, 2022


Do holidays change subjective sleep length or sleep debt in shift work disorder?

In shift work disorder (SWD), disturbed sleep acutely impairs employees’ recovery, but little attention has been paid to sleep during longer recovery periods. We examined how holidays affect self-estimated sleep length, sleep debt, and recovery in cases of SWD. Twenty-one shift workers with questionnaire-based SWD and nine reference cases without SWD symptoms completed a questionnaire […]

Related Product: MotionWatch

Publication Date: February 15, 2022


Chronic circadian disruption on a high-fat diet impairs glucose tolerance

Background Nearly 14% of Americans experience chronic circadian disruption due to shift work, increasing their risk of obesity, diabetes, and other cardiometabolic disorders. These disorders are also exacerbated by modern eating habits such as frequent snacking and consumption of high-fat foods. Methods We investigated the effects of recurrent circadian disruption (RCD) on glucose metabolism in […]

Related Product: MotionWatch

Publication Date: February 9, 2022


Cross-sectional study of intraocular cataract lens replacement, circadian rest-activity rhythms and sleep quality in older adults

Study objectives: Age-related cataract decreases light transmission at the most sensitive spectrum for circadian photoentrainment, with negative ramifications for human health. Here, we assessed whether intraocular lens replacement (IOL) in older patients with previous cataract was associated with increased stability and amplitude of circadian rest-activity rhythms, and sleep quality. Methods: Our cross-sectional study included sixteen […]

Related Product: MotionWatch

Publication Date: January 27, 2022


An exploratory study of associations between sleep timing variability and cardiometabolic health in middle-aged adults with type 2 diabetes mellitus

Sleep is increasingly recognised as an important risk factor for metabolic disease, and as an important influence on severity in established metabolic disease. Recent evidence suggests that sleep timing variability (the day-to-day fluctuations of sleep timing) may be an important factor in metabolic diseases such as type 2 diabetes mellitus. In the current study, we […]

Related Product: MotionWatch

Publication Date: January 11, 2022


Effects of Circadian Phase Tailored Light Therapy on Sleep, Mood, and Cognition in Alzheimer’s Disease: Preliminary Findings in a Pivotal Study

It is shown that the circadian system is affected in patients with Alzheimer’s disease (AD) even at an early stage of the disease and that such dysfunction may be detrimental to sleep, mood, and cognitive functioning. Light is a strong central  modulator of the circadian rhythms and is potentially beneficial to mood and cognitive functioning […]

Related Product: MotionWatch

Publication Date: January 6, 2022


More than sleep and wake disturbances: an actigraphic study showing the sleep-wake pattern dysregulation in epilepsy

Objective This study aimed to assess the sleep-wake pattern in patients with epilepsy compared to controls. Methods Patients with epilepsy and controls underwent a 14-day actigraphic recording to evaluate the rest-activity cycle. A sleep medicine interview was performed to exclude conditions interfering with the sleep-wake cycle in both patients and controls. Patients presenting seizures during […]

Related Product: MotionWatch

Publication Date: November 30, 2021


The influence of integrative lighting on sleep and cognitive functioning of shift workers during the morning shift in an assembly plant

It is well known that exposure to light at the right time of the day is important to synchronise our circadian rhythm and enhance cognitive functioning. There is, however, a lack of field studies investigating which lighting characteristics are necessary to improve sleep and cognitive functioning. A controlled field study with 80 shift workers was […]

Related Product: MotionWatch

Publication Date: November 11, 2021


Extracting Circadian and Sleep Parameters from Longitudinal Data in Schizophrenia for the Design of Pragmatic Light Interventions

Sleep and circadian rhythm dysfunction is prevalent in schizophrenia, is associated with distress and poorer clinical status, yet remains an under-recognized therapeutic target. The development of new therapies requires the identification of the primary drivers of these abnormalities. Understanding of the regulation of sleep-wake timing is now sufficiently advanced for mathematical model-based analyses to identify […]

Related Product: MotionWatch

Publication Date: November 10, 2021


How Smart Is It to Go to Bed with the Phone? The Impact of Short-Wavelength Light and Affective States on Sleep and Circadian Rhythms

Previously, we presented our preliminary results (N = 14) investigating the effects of short-wavelength light from a smartphone during the evening on sleep and circadian rhythms (Höhn et al., 2021). Here, we now demonstrate our full sample (N = 33 men), where polysomnography and body temperature were recorded during three experimental nights and subjects read […]

Related Product: MotionWatch

Publication Date: October 28, 2021


The actigraphic documentation of circadian sleep-wake rhythm dysregulation in Myotonic Dystrophy Type 1

Study Objectives The present study aimed at identifying the sleep-wake rhythm in patients with myotonic dystrophy type 1 (DM1) compared to healthy controls. Methods Patients with genetic diagnosis of DM1 and healthy controls underwent a 7-day actigraphic recording and filled out a daily sleep diary to evaluate the sleep-wake rhythm. All participants underwent a physical […]

Related Product: MotionWatch

Publication Date: October 15, 2021


Diurnal variations of resting-state fMRI data: A graph-based analysis

Circadian rhythms synchronize a variety of physiological processes ranging from neural activity and hormone secretion to sleep cycles and feeding habits. Despite significant diurnal variation, time-of-day (TOD) is rarely recorded or analyzed in human brain research. Moreover, sleep-wake patterns, diurnal preferences, and daytime alertness vary across individuals, known as sleep chronotypes. Here, we performed graph-theory […]

Related Product: MotionWatch

Publication Date: October 12, 2021


Event-related desynchronization in motor imagery with EEG neurofeedback in the context of declarative interference and sleep

Motor imagery (MI) in combination with neurofeedback (NF) is a promising supplement to facilitate the acquisition of motor abilities and the recovery of impaired motor abilities following brain injuries. However, the ability to control MI NF is subject to a wide range of inter-individual variability. A substantial number of users experience difficulties in achieving good […]

Related Product: MotionWatch

Publication Date: October 12, 2021


Effects of the selective orexin-2 receptor antagonist JNJ-48816274 on sleep initiated in the circadian wake maintenance zone: a randomised trial

The effects of orexinergic peptides are diverse and are mediated by orexin-1 and orexin-2 receptors. Antagonists that target both receptors have been shown to promote sleep initiation and maintenance. Here, we investigated the role of the orexin-2 receptor in sleep regulation in a randomised, double-blind, placebo-controlled, three-period crossover clinical trial using two doses (20 and […]

Related Product: MotionWatch

Publication Date: October 9, 2021


Rest activity rhythms characteristics of breast cancer women following endocrine therapy

Rest-activity rhythm (RAR) disruptions are frequently associated with chemotherapy in breast cancer (BC), but they are less known in BC with endocrine therapy (ET). The aim of this ancillary study was to characterize the RAR and estimated sleep characteristics from actigraphy in BC patients either treated (ET+) or untreated with ET (ET−), compared to healthy […]

Related Product: MotionWatch

Publication Date: October 8, 2021


A Multidisciplinary Prematurity Research Cohort Study

Background Worldwide, 10% of babies are born preterm, defined as a live birth before 37 weeks of gestation. Preterm birth is the leading cause of neonatal death, and survivors face lifelong risks of adverse outcomes. New approaches with large sample sizes are needed to identify strategies to predict and prevent preterm birth. The primary aims […]

Related Product: MotionWatch

Publication Date: September 29, 2021


Effects of 2-hour nighttime nap on melatonin concentration and alertness during 12-hour simulated night work

A nighttime nap is expected to mitigate melatonin suppression during night work by blocking light input to the retina, but it is unclear. In the present study, we investigated the effects of a nap break on melatonin level, subjective sleepiness, and vigilance performance during simulated night work. Eleven healthy young males (mean ± SD age: […]

Related Product: MotionWatch

Publication Date: September 27, 2021


Are we still in the dark? A systematic review on personal daily light exposure, sleep-wake rhythm, and mood in healthy adults from the general population

Insufficient light exposure is assumed to be related to a wide array of health problems, though few studies focus on the role of whole-day light exposure in the habitual setting in the development of these health problems. The current review aims to describe the association between personal light exposure in the habitual setting and sleep-wake […]

Related Product: MotionWatch

Publication Date: August 19, 2021


Circadian rhythm and quality of life in older adults

Sleep is critical to physical and mental health for people of all ages, but older adults are particularly vulnerable to the consequences of poor sleep health. The purpose of this pilot study was to explore patterns of sleep and the relationships between circadian rhythm disorders and quantity of life in 34 community-dwelling older adults. Participants […]

Related Product: MotionWatch

Publication Date: June 17, 2021


Time-of-day effects on objective and subjective short-term memory task performance

The time-of-day along with the synchrony effect (better performance at optimal times of the day according to the chronotype) on the cognitive performance has been well established in previous research. This influence is mediated by both circadian and homeostatic processes consistent with the Borbély two-process model. This experiment focused on the objective and subjective performance […]

Related Product: MotionWatch

Publication Date: June 14, 2021


Efficacy of early warning signals and spectral periodicity for predicting transitions in bipolar patients: An actigraphy study

Early-warning signals (EWS) have been successfully employed to predict transitions in research fields such as biology, ecology, and psychiatry. The predictive properties of EWS might aid in foreseeing transitions in mood episodes (i.e. recurrent episodes of mania and depression) in bipolar disorder (BD) patients. We analyzed actigraphy data assessed during normal daily life to investigate […]

Related Product: MotionWatch

Publication Date: June 7, 2021


MotionWatch 8 Wrist Actimetry Data Analysis: from ambulatory recording to real life monitoring

On the National Sleep Research Resource (NSRR) platform, there’s a year’s worth in real-life wrist actigraphy data using a Motionwatch8. The data analysis suggested in this paper reveals a data structure that allows the design of parameters to be used in real life monitoring and may drive the developments of devices. The analysis is totally […]

Related Product: MotionWatch

Publication Date: May 13, 2021


Different Circadian Rest-Active Rhythms in Kleine-Levin Syndrome: A prospective and case-control study

Study objectives Kleine-Levin-syndrome (KLS) is a rare recurrent hypersomnia. Our study aimed at monitoring the movements of patients with KLS using actigraphy and evaluating their circadian rhythm. Methods Twenty young patients with KLS and 14 age-matched controls were recruited. Each individual wore an actigraphy for more than 6 months to monitor at least two attacks. […]

Related Product: MotionWatch

Publication Date: April 14, 2021


Sleep deprivation therapy to reset the circadian pacemaker in a non-24-hour sleep-wake disorder: a case report

Non-24-hour sleep-wake disorder (N24SWD) is one of several chronic circadian rhythm sleep-wake disorders (CRSWDs). It is defined as progressive daily shifts in sleep onset and wake times. It mainly affects sight-impaired persons, is relatively rare in sighted patients, and is difficult to treat, with no guidelines. We report a case of N24SWD in a sighted […]

Related Product: MotionWatch

Publication Date: April 1, 2021


Quantifying Circadian Aspects of Mobility-Related Behavior in Older Adults by Body-Worn Sensors—An “Active Period Analysis”

Disruptions of circadian motor behavior cause a significant burden for older adults as well as their caregivers and often lead to institutionalization. This cross-sectional study investigates the association between mobility-related behavior and subjectively rated circadian chronotypes in healthy older adults. The physical activity of 81 community-dwelling older adults was measured over seven consecutive days and […]

Related Product: MotionWatch

Publication Date: March 18, 2021


Sex Differences in Rest-Activity Circadian Rhythm in Patients With Metabolic Syndrome

Rest-Activity circadian Rhythm (RAR) can be used as a marker of the circadian timing system. Recent studies investigated the relationship between irregular circadian rhythms and cardiovascular risk factors such as hypertension, obesity, and dyslipidemia. These factors are related to the Metabolic Syndrome (MS), a clustering of metabolic risk factors that increases the risk of several […]

Related Product: MotionWatch

Publication Date: March 18, 2021


Weekly, seasonal and chronotype‐dependent variation of Dim‐Light Melatonin Onset

In humans, the most important zeitgeber for entrainment is light. Laboratory studies have shown that meaningful changes in light exposure lead to phase shifts in markers of the circadian clock. In natural settings, light is a complex signal varying with external conditions and individual behaviors; nonetheless, phase of entrainment is assumed to be fairly stable. […]

Related Product: MotionWatch

Publication Date: February 20, 2021


Temporal organisation of the brain’s intrinsic motor network: The relationship with circadian phenotype and motor performance

Background Functional connectivity (FC) of the motor network (MN) is often used to investigate how intrinsic properties of the brain are associated with motor abilities and performance. In addition, the MN is a key feature in clinical work to map the recovery after stroke and aid the understanding of neurodegenerative disorders. Time of day variation […]

Related Product: MotionWatch

Publication Date: February 9, 2021


Can actigraphy be used to define lithium response dimensions in bipolar disorders?

Background: Actigraphy is commonly used in case-control studies to explore sleep-wake patterns and circadian rhythmicity in bipolar disorders (BD). However, there is limited ecological research regarding actigraphy parameters associated with response to lithium (Li_Resp). Methods: Outpatients with BD-I (n=70) and BD-II (n=20) who were all prescribed prophylactic Li undertook 21 consecutive days of actigraphy recording. […]

Related Product: MotionWatch

Publication Date: February 2, 2021


A brief report of sleep and circadian rhythm quotas in a population of dog owners in North Carolina USA

Objectives To characterize sleep and circadian rhythms of a sample population of healthy, dog-owning adults from North Carolina, USA. Methods Actigraphy was used to analyze sleep-wake patterns in forty-two dog owners from the Raleigh area in North Carolina. Sleep quotas, including sleep duration, efficiency, and fragmentation were measured alongside a Non-parametric Circadian Rhythms Analysis (NPCRA) […]

Related Product: MotionWatch

Publication Date: January 22, 2021


Sleep, Circadian Rhythmicity and Response to Chronotherapy in University Students: Tips from Chronobiology Practicals

Chronobiology is not routinely taught to biology or medical students in most European countries. Here we present the results of the chronobiology practicals of a group of students of the University of Padova, with a view to highlight some interesting features of this group, and to share a potentially interesting cross-faculty teaching experience. Thirty-eight students […]

Related Product: PRO-Diary

Publication Date: January 21, 2021


Circadian Patterns of Patients with Type 2 Diabetes and Obstructive Sleep Apnea

Sleep apnea, a condition that modifies sleep and circadian rhythms, is highly prevalent in patients with diabetes. However, it is not known if there is an association between sleep apnea, circadian alterations and glycemic regulation in this type of patient. Here, a polysomnographic study was carried out on 21 women and 25 men (mean age […]

Related Product: MotionWatch

Publication Date: January 11, 2021


Sleep− wake cycle dysregulation in idiopathic REM sleep behaviour disorder

Alteration of the circadian sleep−wake rhythm has been suggested in patients affected by idiopathic rapid eye movement sleep behaviour disorder. Because actigraphy is the validated instrument to monitor the sleep−wake cycle, the aim of the present study was to investigate the circadian sleep−wake rhythm in patients with idiopathic rapid eye movement sleep behaviour disorder compared […]

Related Product: MotionWatch

Publication Date: December 1, 2020


Effect of vestibular stimulation using a rotatory chair in human rest/activity rhythm

The vestibular system is responsible for sensing every angular and linear head acceleration, mainly during periods of motor activity. Previous animal and human experiments have shown biological rhythm disruptions in small rodents exposed to a hypergravity environment, but also in patients with bilateral vestibular loss compared to a control population. This raised the hypothesis of […]

Related Product: MotionWatch

Publication Date: September 26, 2020


Timed physical exercise does not influence circadian rhythms and glucose tolerance in rotating night shift workers: The EuRhythDia study

Objectives: Night shift workers are at cardiometabolic risk due to circadian misalignment. We investigated whether infrequent exercise before each night shift that intentionally would not improve physical performance improves glucose tolerance and 24-h blood pressure profiles and synchronizes circadian rhythms of melatonin and cortisol in rotating night shift workers. Methods: A total of 24 rotating […]

Related Product: MotionWatch

Publication Date: September 25, 2020


Prediction of individual differences in circadian adaptation to night work among older adults: application of a mathematical model using individual sleep-wake and light exposure data

Circadian misalignment remains a distinct challenge for night shift workers. Variability in individual sleep-wake/light-dark patterns might contribute to individual differences in circadian alignment in night shift workers. In this simulation study, we compared the predicted phase shift from a mathematical model of the effect of light on the human circadian pacemaker to the observed melatonin […]

Related Product: MotionWatch

Publication Date: September 6, 2020


Disturbances of Continuous Sleep and Circadian Rhythms Account for Behavioral Difficulties in Children with Autism Spectrum Disorder

Sleep disorders are among the most common comorbidities in children with Autism Spectrum Disorder (ASD), and subjectively defined sleep disturbances have been related to ASD symptom severity. However, no study has investigated the differential impact of objectively measured sleep and circadian rhythm disturbances on behavioral difficulties in this population. Fifty-two children with ASD aged 3–10 […]

Related Product: MotionWatch

Publication Date: June 24, 2020


Rest-activity rhythm in breast cancer survivors: an update based on non-parametric indices

Recently we evaluated by actigraphy the rest-activity circadian rhythm (RAR) in breast cancer (BC) survivors at 5 years from primary diagnosis, as well as in a control group with similar age and body mass index (BMI). RAR, analyzed by Cosinor method, resulted significantly different in BC survivors compared to healthy subjects: BC survivors showed lower […]

Related Product: MotionWatch

Publication Date: April 24, 2020


Sleep-Wake Cycle in Alzheimer’s Disease Is Associated with Tau Pathology and Orexin Dysregulation

Background:Alzheimer’s disease (AD) is the most common form of dementia. It is mainly characterized by a progressive deterioration of cognition, but sleep-wake cycle disturbances frequently occur. Irregular sleep-wake cycle, insomnia, and daytime napping usually occur in patients with AD in the course of the disease. Objective:The aim of the present study was to verify the […]

Related Product: MotionWatch

Publication Date: February 10, 2020


Disruption in daily eating-fasting and activity-rest cycles in Indian adolescents attending school.

A lifestyle with erratic eating patterns and habits predisposes youngsters to obesity. Through a two-phase feasibility study among Indian students living in the Delhi area, we longitudinally examined the following: (1) the daily eating-fasting cycles of students (N = 34) in school and college using smartphones as they transition from high school (aged 13–15 years; […]

Related Product: MotionWatch

Publication Date: January 10, 2020


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